How do stem cells help treat cancer disease?
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Are you referring to treat as in stem cell transplant? It?s actually kind of interesting- the stem cell transplant (or its predecessor, the bone marrow transplant) are not actually the treatment. The stem cell transplant is the rescue from the treatment, which is extremely high dose chemotherapy and total body irradiation.
For a stem cell transplant, stem cells can come from the peripheral (circulating) blood of another person, or from umbilical cord blood. The person receiving the stem cells undergoes up two two weeks of conditioning- this is the high dose chemotherapy and radiation that wipes out the cancer cells AND the good cells. It basically destroys the bone marrow. The stem cells are then infused into the patient and once they settle in, they start reproducing and making what is hopefully clean bone marrow.
Stem cells are immature cells found in the bone marrow, blood stream, and in umbilical cords. These immature stem cells later develop into blood cells. Since stem cells can be damaged in certain cancer treatments. Stem cells can be used in bone marrow transplantation and peripheral blood stem cell transplantation. Both of these procedures are used to restore stem cells that have been destroyed by high dose chemotherapy. These treatments using stem cells may also be used for patients who have had radiation treatment for their cancer. Stem cells are used in a type of cancer treatment called autologous stem cell rescue. In this procedure, your own peripheral stem cells and bone marrow are used to overcome the bone marrow destroying effects of radiation and high dose chemotherapy.
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